Managing unpredictable challenge of a metastatic nodule in radiation treatment field—a case report

Abstract Background Despite the high prevalence of locally advanced head and neck cancer, treatment failure in form a cutaneous deposit field during radiation is not common. There has never been cytology-proven published case marginal region radiotherapy. Case presentation A 51-year-old male patient was diagnosed with squamous cell carcinoma left tonsillar fossa. After partial response to induction chemotherapy, treated definitive chemo-radiotherapy. 23rd fractionation radiotherapy, there clinical progression solitary skin nodule within field, which further an electron boost total dose 70 Gy followed by palliative chemotherapy. Conclusion During chemoradiotherapy, outside high-dose common, had described. Our demonstrates importance performing thorough examinations on weekly basis, only for toxicity assessment but also response.